Name | GPA 512 |
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Description | The orally bioavailable prodrug of Galiellalactone, a direct inhibitor of STAT3, prevents the transcription of STAT3 regulated genes; increases the plasma exposure of the active parent compound 20-fold compared to Galiellalactone; significantly reduces tumor growth in DU145 xenograft tumors. |
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References | References 1. Escobar Z, et al. J Med Chem. 2016 May 26;59(10):4551-62. View Related Products by Target STAT |
Molecular Formula | C17H25NO6S |
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Molecular Weight | 371.448 |