2086328-94-9
2086328-94-9 structure
- Name: NBD-14107
- Chemical Name: NBD-14107
- CAS Number: 2086328-94-9
- Molecular Formula: C17H15ClF2N4O2S
- Molecular Weight: 412.84
- Create Date: 2020-01-20 15:41:56
- Modify Date: 2023-02-25 19:25:45
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A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction; exhibits antiviral activity against a large panel of HIV-1 Env-pseudotyped viruses representing diverse subtypes of clinical isolates with mean EC50 of 0.49 uM; also inhibits HIV-1 RT with IC50 of 8.4 uM; exhibits improving the potency, toxicity, and ADMET profile compared with NBD-14010. HIV Preclinical
| Name | NBD-14107 |
|---|
| Description | A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction; exhibits antiviral activity against a large panel of HIV-1 Env-pseudotyped viruses representing diverse subtypes of clinical isolates with mean EC50 of 0.49 uM; also inhibits HIV-1 RT with IC50 of 8.4 uM; exhibits improving the potency, toxicity, and ADMET profile compared with NBD-14010. HIV Preclinical |
|---|---|
| References | References 1. Curreli F, et al. J Med Chem. 2017 Apr 13;60(7):3124-3153. View Related Products by Target HIV HIV |
| Molecular Formula | C17H15ClF2N4O2S |
|---|---|
| Molecular Weight | 412.84 |