402564-79-8
402564-79-8 structure
- Name: BIO 8898
- Chemical Name: BIO 8898
- CAS Number: 402564-79-8
- Molecular Formula: C53H64N8O6
- Molecular Weight: 909.145
- Create Date: 2020-01-11 16:33:51
- Modify Date: 2025-08-25 15:28:36
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BIO 8898 is a synthetic, CD40-CD154 co-stimulatory interaction inhibitor that inhibits the TNF family cytokine CD40L binding to CD40-Ig with a potency of IC50=25 uM; inhibits CD40L-dependent apoptosis in a cellular assay.
| Name | BIO 8898 |
|---|
| Description | BIO 8898 is a synthetic, CD40-CD154 co-stimulatory interaction inhibitor that inhibits the TNF family cytokine CD40L binding to CD40-Ig with a potency of IC50=25 uM; inhibits CD40L-dependent apoptosis in a cellular assay. |
|---|---|
| References | References 1. Silvian LF, et al. ACS Chem Biol. 2011 Jun 17;6(6):636-47. 2. Ganesan L, et al. Pharmazie. 2012 May;67(5):374-9. View Related Products by Target Other Targets |
| Molecular Formula | C53H64N8O6 |
|---|---|
| Molecular Weight | 909.145 |