BIO 8898
Modify Date: 2025-08-25 15:28:36
BIO 8898 structure
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Common Name | BIO 8898 | ||
|---|---|---|---|---|
| CAS Number | 402564-79-8 | Molecular Weight | 909.145 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C53H64N8O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BIO 8898BIO 8898 is a synthetic, CD40-CD154 co-stimulatory interaction inhibitor that inhibits the TNF family cytokine CD40L binding to CD40-Ig with a potency of IC50=25 uM; inhibits CD40L-dependent apoptosis in a cellular assay. |
| Name | BIO 8898 |
|---|
| Description | BIO 8898 is a synthetic, CD40-CD154 co-stimulatory interaction inhibitor that inhibits the TNF family cytokine CD40L binding to CD40-Ig with a potency of IC50=25 uM; inhibits CD40L-dependent apoptosis in a cellular assay. |
|---|---|
| References | References 1. Silvian LF, et al. ACS Chem Biol. 2011 Jun 17;6(6):636-47. 2. Ganesan L, et al. Pharmazie. 2012 May;67(5):374-9. View Related Products by Target Other Targets |
| Molecular Formula | C53H64N8O6 |
|---|---|
| Molecular Weight | 909.145 |
| InChIKey | WJYLSDLKLWXYML-UHFFFAOYSA-N |
| SMILES | O=C(NCc1cccc(-c2ccccc2)c1)c1cc(-c2cc(C(=O)NC(C(=O)O)C3CCCCC3)nc(C(=O)N3CCCC3CN3CCCC3)c2)cc(C(=O)N2CCCC2CN2CCCC2)n1 |