906718-66-9
906718-66-9 structure
- Name: NSC260594
- Chemical Name: NSC260594
- CAS Number: 906718-66-9
- Molecular Formula: C29H24N6O3
- Molecular Weight: 504.55
- Catalog: Signaling Pathways Anti-infection HIV
- Create Date: 2020-01-20 10:32:56
- Modify Date: 2024-04-09 20:44:55
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NSC260594 (NSC 260594) is a specific inhibitor of HIV-1 RNA packaging, which involves preventing the interaction of Gag with SL3 by stabilizing this small RNA stem-loop which then leads to stabilization of the global packaging signal region (psi or ψ); specifically blocks HIV-1 RNA encapsidation, binds to HIV-1 gRNA and exhibits potent antiviral activity; NSC260594 also is a small molecule inhibitor of the Escherichia coli condensin MukBEF, affects MukB directly.
| Name | NSC260594 |
|---|
| Description | NSC260594 (NSC 260594) is a specific inhibitor of HIV-1 RNA packaging, which involves preventing the interaction of Gag with SL3 by stabilizing this small RNA stem-loop which then leads to stabilization of the global packaging signal region (psi or ψ); specifically blocks HIV-1 RNA encapsidation, binds to HIV-1 gRNA and exhibits potent antiviral activity; NSC260594 also is a small molecule inhibitor of the Escherichia coli condensin MukBEF, affects MukB directly. |
|---|---|
| References | References 1. Ingemarsdotter CK, et al. Retrovirology. 2018 Mar 14;15(1):25. 2. Zhao H, et al. ACS Infect Dis. 2018 Oct 22. doi: 10.1021/acsinfecdis.8b00222. View Related Products by Target HIV |
| Molecular Formula | C29H24N6O3 |
|---|---|
| Molecular Weight | 504.55 |