NSC260594
Modify Date: 2025-09-18 17:04:02
NSC260594 structure
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Common Name | NSC260594 | ||
|---|---|---|---|---|
| CAS Number | 906718-66-9 | Molecular Weight | 504.55 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H24N6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NSC260594NSC260594 (NSC 260594) is a specific inhibitor of HIV-1 RNA packaging, which involves preventing the interaction of Gag with SL3 by stabilizing this small RNA stem-loop which then leads to stabilization of the global packaging signal region (psi or ψ); specifically blocks HIV-1 RNA encapsidation, binds to HIV-1 gRNA and exhibits potent antiviral activity; NSC260594 also is a small molecule inhibitor of the Escherichia coli condensin MukBEF, affects MukB directly. |
| Name | NSC260594 |
|---|
| Description | NSC260594 (NSC 260594) is a specific inhibitor of HIV-1 RNA packaging, which involves preventing the interaction of Gag with SL3 by stabilizing this small RNA stem-loop which then leads to stabilization of the global packaging signal region (psi or ψ); specifically blocks HIV-1 RNA encapsidation, binds to HIV-1 gRNA and exhibits potent antiviral activity; NSC260594 also is a small molecule inhibitor of the Escherichia coli condensin MukBEF, affects MukB directly. |
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| References | References 1. Ingemarsdotter CK, et al. Retrovirology. 2018 Mar 14;15(1):25. 2. Zhao H, et al. ACS Infect Dis. 2018 Oct 22. doi: 10.1021/acsinfecdis.8b00222. View Related Products by Target HIV |
| Molecular Formula | C29H24N6O3 |
|---|---|
| Molecular Weight | 504.55 |
| InChIKey | SDVVSJQTYKFAFR-UHFFFAOYSA-N |
| SMILES | Cn1ccc(=Nc2ccc(NC(=O)c3ccc(N=c4ccn(C)c5ccc([N+](=O)[O-])cc45)cc3)cc2)cc1 |