2241732-30-7
2241732-30-7 structure
- Name: BTK inhibitor 10
- Chemical Name: BTK-030
- CAS Number: 2241732-30-7
- Molecular Formula: C25H23N5O3
- Molecular Weight: 441.491
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Btk
- Create Date: 2020-01-11 18:06:58
- Modify Date: 2025-08-26 12:04:54
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BTK-030 is a novel BTK inhibitor.
| Name | BTK-030 |
|---|
| Description | BTK-030 is a novel BTK inhibitor. |
|---|---|
| Related Catalog | |
| Target |
IC50: Bruton kinase (BTK)[1] |
| In Vivo | BTK inhibitor 10 (oral gavage; 30 mg/kg; 21 days; once daily) has a significant improvement in arthritis symptoms in CIA mice. The damage of each of the 4 paws in mice is divided into 0-4 to calculate the total score of the limbs. After 21 days’ oral treatment, BTK030 reduces the arthritic score to 3.62 while the control group shows a value of 8.33[1]. Animal Model: DBA/1J mice injected with collagen as a CIA model[1] Dosage: 30 mg/kg Administration: oral gavage; 21 days; once daily Result: Decreased arthritis scores significantly when it compares to control group. |
| References |
| Molecular Formula | C25H23N5O3 |
|---|---|
| Molecular Weight | 441.491 |