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1424832-57-4

1424832-57-4 structure
1424832-57-4 structure
  • Name: (2S,3S)-E1R
  • Chemical Name: (2S,3S)-E1R
  • CAS Number: 1424832-57-4
  • Molecular Formula: C13H16N2O2
  • Molecular Weight: 232.28
  • Catalog: Signaling Pathways GPCR/G Protein Sigma Receptor
  • Create Date: 2020-01-23 19:42:51
  • Modify Date: 2024-01-09 16:36:02
  • (2S,3S)-E1R (Compound 2d) is an enantiomer of E1R. (2S,3S)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for the treatment of cognition/memory disorders[1].

Name (2S,3S)-E1R
Description (2S,3S)-E1R (Compound 2d) is an enantiomer of E1R. (2S,3S)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for the treatment of cognition/memory disorders[1].
Related Catalog
In Vitro Sigma-1 receptor plays an important role in neuronal plasticity, a process implicated in the pathophysiology of neuropsychiatric diseases, such as Alzheimer’s disease, major depressive disorders, and schizophrenia[1].
References

[1]. Veinberg G, et al. Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor. Bioorg Med Chem. 2013 May 15;21(10):2764-71.

Molecular Formula C13H16N2O2
Molecular Weight 232.28
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