(2S,3S)-E1R

Modify Date: 2025-08-25 10:53:59

(2S,3S)-E1R Structure
(2S,3S)-E1R structure
 Common Name (2S,3S)-E1R
CAS Number 1424832-57-4 Molecular Weight 232.28
Density N/A Boiling Point N/A
Molecular Formula C13H16N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (2S,3S)-E1R


(2S,3S)-E1R (Compound 2d) is an enantiomer of E1R. (2S,3S)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for the treatment of cognition/memory disorders[1].

 Names

Name (2S,3S)-E1R

 (2S,3S)-E1R Biological Activity

Description (2S,3S)-E1R (Compound 2d) is an enantiomer of E1R. (2S,3S)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for the treatment of cognition/memory disorders[1].
Related Catalog
In Vitro Sigma-1 receptor plays an important role in neuronal plasticity, a process implicated in the pathophysiology of neuropsychiatric diseases, such as Alzheimer’s disease, major depressive disorders, and schizophrenia[1].
References

[1]. Veinberg G, et al. Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor. Bioorg Med Chem. 2013 May 15;21(10):2764-71.

 Chemical & Physical Properties

Molecular Formula C13H16N2O2
Molecular Weight 232.28
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