1044511-01-4

1044511-01-4 structure

Name: Benralizumab
Chemical Name: Benralizumab
CAS Number: 1044511-01-4
Molecular Formula: C₆₄₉₂H₁₀₀₆₀N₁₇₂₄O₂₀₂₈S₄₂
Molecular Weight: 146054.0
Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
Create Date: 2020-01-24 00:12:51
Modify Date: 2024-01-05 17:17:39
Benralizumab (MEDI-563) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used to treat severe eosinophilic asthma[1].

Name	Benralizumab

Description	Benralizumab (MEDI-563) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used to treat severe eosinophilic asthma[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Interleukin Related Research Areas >> Inflammation/Immunology
Target	IL-5Rα[1]
References	[1]. Menzies-Gow A, et al. Corticosteroid tapering with benralizumab treatment for eosinophilic asthma: PONENTE Trial. ERJ Open Res. 2019 Sep 25;5(3). pii: 00009-2019.

Molecular Formula	C₆₄₉₂H₁₀₀₆₀N₁₇₂₄O₂₀₂₈S₄₂
Molecular Weight	146054.0