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675104-49-1

675104-49-1 structure
675104-49-1 structure
  • Name: DSHS00884
  • Chemical Name: DSHS00884
  • CAS Number: 675104-49-1
  • Molecular Formula: C12H12N4O2S2
  • Molecular Weight: 308.38
  • Catalog: Signaling Pathways Anti-infection Filovirus
  • Create Date: 2020-01-23 15:27:51
  • Modify Date: 2024-02-02 10:32:19
  • DSHS00884 is a potent human papillomavirus E6 inhibitor with an IC50 of 10 μM[1].

Name DSHS00884
Description DSHS00884 is a potent human papillomavirus E6 inhibitor with an IC50 of 10 μM[1].
Related Catalog
Target

IC50: 10 μM (human papillomavirus E6)[1]

In Vitro DSHS00884 stabilizes p53 levels in HPV-positive cells by blocking E6-mediated p53 degradation with an IC50 of 2.5-25 μM[1].
References

[1]. Malecka KA, et al. Identification and characterization of small molecule human papillomavirus E6 inhibitors. ACS Chem Biol. 2014 Jul 18;9(7):1603-12.

Molecular Formula C12H12N4O2S2
Molecular Weight 308.38
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