DSHS00884

Modify Date: 2025-09-20 11:45:50

DSHS00884 Structure
DSHS00884 structure
Common Name DSHS00884
CAS Number 675104-49-1 Molecular Weight 308.38
Density N/A Boiling Point N/A
Molecular Formula C12H12N4O2S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DSHS00884


DSHS00884 is a potent human papillomavirus E6 inhibitor with an IC50 of 10 μM[1].

 Names

Name DSHS00884

 DSHS00884 Biological Activity

Description DSHS00884 is a potent human papillomavirus E6 inhibitor with an IC50 of 10 μM[1].
Related Catalog
Target

IC50: 10 μM (human papillomavirus E6)[1]

In Vitro DSHS00884 stabilizes p53 levels in HPV-positive cells by blocking E6-mediated p53 degradation with an IC50 of 2.5-25 μM[1].
References

[1]. Malecka KA, et al. Identification and characterization of small molecule human papillomavirus E6 inhibitors. ACS Chem Biol. 2014 Jul 18;9(7):1603-12.

 Chemical & Physical Properties

Molecular Formula C12H12N4O2S2
Molecular Weight 308.38
InChIKey VWFIHGWHMXSTAO-UHFFFAOYSA-N
SMILES C=CCn1c(CSc2ccccc2[N+](=O)[O-])n[nH]c1=S
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