DC Chemicals Limited
China
Product Name: hDDAH-1-IN-1 TFA
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Purity: 98.0%
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Contact: Tony Cao

1229238-70-3

1229238-70-3 structure

1229238-70-3 structure

Name: hDDAH-1-IN-1 TFA
Chemical Name: hDDAH-1-IN-1 TFA
CAS Number: 1229238-70-3
Molecular Formula: C₁₂H₂₂F₆N₄O₅
Molecular Weight: 416.32
Catalog: Research Areas Cancer
Create Date: 2020-01-23 17:55:51
Modify Date: 2024-01-09 18:45:54
hDDAH-1-IN-1 TFA (compound 8a) is a potent and selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1), with a Ki of 18 µM[1].

Name	hDDAH-1-IN-1 TFA

Description	hDDAH-1-IN-1 TFA (compound 8a) is a potent and selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1), with a Ki of 18 µM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	hDDAH-1-IN-1 TFA potently inhibits hDDAH-1 (Ki = 18 µM) without significantly affecting NOSs and arginase[1].
References	[1]. Lunk I, et al. Discovery of N-(4-Aminobutyl)-N'-(2-methoxyethyl)guanidine as the First Selective, Nonamino Acid, Catalytic Site Inhibitor of Human Dimethylarginine Dimethylaminohydrolase-1 (hDDAH-1). J Med Chem. 2019 Dec 31.

Molecular Formula	C₁₂H₂₂F₆N₄O₅
Molecular Weight	416.32