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1229238-70-3

1229238-70-3 structure
1229238-70-3 structure
  • Name: hDDAH-1-IN-1 TFA
  • Chemical Name: hDDAH-1-IN-1 TFA
  • CAS Number: 1229238-70-3
  • Molecular Formula: C12H22F6N4O5
  • Molecular Weight: 416.32
  • Catalog: Research Areas Cancer
  • Create Date: 2020-01-23 17:55:51
  • Modify Date: 2024-01-09 18:45:54
  • hDDAH-1-IN-1 TFA (compound 8a) is a potent and selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1), with a Ki of 18 µM[1].

Name hDDAH-1-IN-1 TFA
Description hDDAH-1-IN-1 TFA (compound 8a) is a potent and selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1), with a Ki of 18 µM[1].
Related Catalog
In Vitro hDDAH-1-IN-1 TFA potently inhibits hDDAH-1 (Ki = 18 µM) without significantly affecting NOSs and arginase[1].
References

[1]. Lunk I, et al. Discovery of N-(4-Aminobutyl)-N'-(2-methoxyethyl)guanidine as the First Selective, Nonamino Acid, Catalytic Site Inhibitor of Human Dimethylarginine Dimethylaminohydrolase-1 (hDDAH-1). J Med Chem. 2019 Dec 31.

Molecular Formula C12H22F6N4O5
Molecular Weight 416.32
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