DC Chemicals Limited
China
Product Name: Imatinib D4
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Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

1134803-16-9

1134803-16-9 structure

1134803-16-9 structure

Name: Imatinib D4
Chemical Name: Imatinib D4
CAS Number: 1134803-16-9
Molecular Formula: C₂₉H₂₇D₄N₇O
Molecular Weight: 497.63
Catalog: Signaling Pathways Autophagy Autophagy
Create Date: 2020-01-23 23:37:51
Modify Date: 2024-01-15 22:10:31
Imatinib D4 (STI571 D4) is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity[1][2].

Name	Imatinib D4

Description	Imatinib D4 (STI571 D4) is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PDGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Bcr-Abl Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Kit
References	[1]. Heinrich MC, et al. Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor. Blood. 2000 Aug 1;96(3):925-32. [2]. Guida T, et al. Sorafenib inhibits imatinib-resistant KIT and platelet-derived growth factor receptor beta gatekeeper mutants. Clin Cancer Res. 2007 Jun 1;13(11):3363-9.

Molecular Formula	C₂₉H₂₇D₄N₇O
Molecular Weight	497.63

Hazard Codes	Xi