| Name | Δ7-sterol 5(6)-desaturase |
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| Synonyms |
EC 1.14.19.20
lathosterol oxidase Δ7-sterol Δ5-dehydrogenase Δ7-sterol 5-desaturase Δ7-sterol-C5(6)-desaturase 5-DES SC5DL (gene name) ERG3 (gene name) |
| Description | This enzyme, found in eukaryotic organisms, catalyses the introduction of a double bond between the C5 and C6 carbons of the B ring of Δ7-sterols, to yield the corresponding Δ5,7-sterols. The enzymes from yeast, plants and vertebrates act on avenasterol, episterol, and lathosterol, respectively. The enzyme is located at the endoplasmic reticulum and is membrane bound. Reaction: a Δ7-sterol + 2 ferrocytochrome b5 + O2 + 2 H+ = a Δ5,7-sterol + 2 ferricytochrome b5 + 2 H2O |
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| No Any Chemical & Physical Properties |