154024-76-7

154024-76-7 structure

Name: Biotin-sar-oh
Chemical Name: MFCD11113162
CAS Number: 154024-76-7
Molecular Formula: C₁₃H₂₁N₃O₄S
Molecular Weight: 315.388
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2020-04-05 23:25:17
Modify Date: 2024-01-17 18:12:46
Biotin-sar-oh is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	MFCD11113162
Synonyms	MFCD11113162 N-Methyl-N-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}glycine Glycine, N-[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]-N-methyl- (+)-Biotin-sarcosine [{5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}(methyl)amino]acetic acid

Description	Biotin-sar-oh is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.