Biotin-sar-oh

Modify Date: 2025-08-30 09:38:52

Use of Biotin-sar-oh

Biotin-sar-oh is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	MFCD11113162
Synonym	More Synonyms

Description	Biotin-sar-oh is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Density	1.3±0.0 g/cm3
Boiling Point	646.1±0.0 °C at 760 mmHg
Molecular Formula	C₁₃H₂₁N₃O₄S
Molecular Weight	315.388
Flash Point	344.5±0.0 °C
Exact Mass	315.125275
LogP	0.32
Vapour Pressure	0.0±0.0 mmHg at 25°C
Index of Refraction	1.549
InChIKey	FCDUPOLHSWBTFL-AUTRQRHGSA-N
SMILES	CN(CC(=O)O)C(=O)CCCCC1SCC2NC(=O)NC21

MFCD11113162

N-Methyl-N-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}glycine

Glycine, N-[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]-N-methyl-

(+)-Biotin-sarcosine

[{5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}(methyl)amino]acetic acid

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