Biotin-sar-oh

Modify Date: 2024-01-17 18:12:46

Biotin-sar-oh Structure
Biotin-sar-oh structure
Common Name Biotin-sar-oh
CAS Number 154024-76-7 Molecular Weight 315.388
Density 1.3±0.0 g/cm3 Boiling Point 646.1±0.0 °C at 760 mmHg
Molecular Formula C13H21N3O4S Melting Point N/A
MSDS N/A Flash Point 344.5±0.0 °C

 Use of Biotin-sar-oh


Biotin-sar-oh is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name MFCD11113162
Synonym More Synonyms

 Biotin-sar-oh Biological Activity

Description Biotin-sar-oh is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

 Chemical & Physical Properties

Density 1.3±0.0 g/cm3
Boiling Point 646.1±0.0 °C at 760 mmHg
Molecular Formula C13H21N3O4S
Molecular Weight 315.388
Flash Point 344.5±0.0 °C
Exact Mass 315.125275
LogP 0.32
Vapour Pressure 0.0±0.0 mmHg at 25°C
Index of Refraction 1.549

 Synonyms

MFCD11113162
N-Methyl-N-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}glycine
Glycine, N-[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]-N-methyl-
(+)-Biotin-sarcosine
[{5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}(methyl)amino]acetic acid
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