2028284-75-3

2028284-75-3 structure

Name: Acid-PEG4-mono-methyl ester
Chemical Name: Acid-PEG4-mono-methyl ester
CAS Number: 2028284-75-3
Molecular Formula: C₁₃H₂₄O₈
Molecular Weight: 308.32
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-10 10:12:23
Modify Date: 2024-01-02 21:19:41
Acid-PEG4-mono-methyl ester is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	Acid-PEG4-mono-methyl ester

Description	Acid-PEG4-mono-methyl ester is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Kanazaki K, et al. Feasibility of poly(ethylene glycol) derivatives as diagnostic drug carriers for tumor imaging. J Control Release. 2016 Mar 28;226:115-23.