Acid-PEG4-mono-methyl ester

Modify Date: 2024-01-02 21:19:41

Acid-PEG4-mono-methyl ester Structure
Acid-PEG4-mono-methyl ester structure
Common Name Acid-PEG4-mono-methyl ester
CAS Number 2028284-75-3 Molecular Weight 308.32
Density N/A Boiling Point N/A
Molecular Formula C13H24O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Acid-PEG4-mono-methyl ester


Acid-PEG4-mono-methyl ester is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name Acid-PEG4-mono-methyl ester

 Acid-PEG4-mono-methyl ester Biological Activity

Description Acid-PEG4-mono-methyl ester is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Kanazaki K, et al. Feasibility of poly(ethylene glycol) derivatives as diagnostic drug carriers for tumor imaging. J Control Release. 2016 Mar 28;226:115-23.

 Chemical & Physical Properties

Molecular Formula C13H24O8
Molecular Weight 308.32
Storage condition 2-8°C