2242464-44-2
2242464-44-2 structure
- Name: BAY 2416964
- Chemical Name: AHR antagonist 3
- CAS Number: 2242464-44-2
- Molecular Formula: C18H18ClN5O3
- Molecular Weight: 387.82
- Catalog: Signaling Pathways Immunology/Inflammation Aryl Hydrocarbon Receptor
- Create Date: 2020-04-05 19:15:05
- Modify Date: 2025-08-25 19:39:37
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AHR antagonist 3 is a 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamide compound and an aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 192, has an IC50 of 341 nM. AHR antagonist 3 has anti-cancer effects[1].
| Name | AHR antagonist 3 |
|---|
| Description | AHR antagonist 3 is a 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamide compound and an aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 192, has an IC50 of 341 nM. AHR antagonist 3 has anti-cancer effects[1]. |
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| Related Catalog | |
| Target |
IC50: 341 nM (Aryl hydrocarbon receptor (AHR))[1] |
| In Vitro | AHR antagonist 3 (Example 192) induces AHR-regulated gene CYP1A1 expression in a human monocytic U937 cells with an IC50 of 4.3 nM[1]. |
| References |
| Density | 1.42±0.1 g/cm3(Predicted) |
|---|---|
| Molecular Formula | C18H18ClN5O3 |
| Molecular Weight | 387.82 |
| Hazard Codes | Xn |
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