1683617-62-0

1683617-62-0 structure

Name: Apcin-A
Chemical Name: Apcin-A
CAS Number: 1683617-62-0
Molecular Formula: C₁₀H₁₄Cl₃N₅O₂
Molecular Weight: 342.61
Catalog: Signaling Pathways Cell Cycle/DNA Damage APC
Create Date: 2020-04-10 16:52:42
Modify Date: 2024-01-10 12:16:33
Apcin-A, an Apcin derivative, is an anaphase-promoting complex (APC) inhibitor. Apcin-A interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A can be used to synthesize the PROTAC CP5V (HY-130257)[1].

Name	Apcin-A

Description	Apcin-A, an Apcin derivative, is an anaphase-promoting complex (APC) inhibitor. Apcin-A interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A can be used to synthesize the PROTAC CP5V (HY-130257)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> APC
References	[1]. Chi JJ, et al. A novel strategy to block mitotic progression for targeted therapy. EBioMedicine. 2019 Oct 25. pii: S2352-3964(19)30677-2.

Molecular Formula	C₁₀H₁₄Cl₃N₅O₂
Molecular Weight	342.61

Hazard Codes	Xi