2252392-53-1

2252392-53-1 structure

Name: Azido-PEG11-alcohol
Chemical Name: Azido-PEG11-alcohol
CAS Number: 2252392-53-1
Molecular Formula: C₂₂H₄₅N₃O₁₁
Molecular Weight: 527.61
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-04 11:03:32
Modify Date: 2024-01-16 12:30:28
Azido-PEG11-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Azido-PEG11-alcohol

Description	Azido-PEG11-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562