Azido-PEG11-alcohol

Modify Date: 2024-01-16 12:30:28

Azido-PEG11-alcohol Structure
Azido-PEG11-alcohol structure
Common Name Azido-PEG11-alcohol
CAS Number 2252392-53-1 Molecular Weight 527.61
Density N/A Boiling Point N/A
Molecular Formula C22H45N3O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG11-alcohol


Azido-PEG11-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG11-alcohol

 Azido-PEG11-alcohol Biological Activity

Description Azido-PEG11-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C22H45N3O11
Molecular Weight 527.61
Storage condition 2-8°C