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1895922-72-1

1895922-72-1 structure
1895922-72-1 structure
  • Name: t-Boc-aminooxy-PEG1-propargyl
  • Chemical Name: Boc-aminooxy-PEG1-propargyl
  • CAS Number: 1895922-72-1
  • Molecular Formula: C10H17NO4
  • Molecular Weight: 215.25
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-08 19:07:22
  • Modify Date: 2024-01-03 20:10:55
  • Boc-aminooxy-PEG1-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Boc-aminooxy-PEG1-propargyl
Synonyms MFCD29764325
Description Boc-aminooxy-PEG1-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

Molecular Formula C10H17NO4
Molecular Weight 215.25
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