t-Boc-aminooxy-PEG1-propargyl

Modify Date: 2024-01-03 20:10:55

t-Boc-aminooxy-PEG1-propargyl Structure
t-Boc-aminooxy-PEG1-propargyl structure
Common Name t-Boc-aminooxy-PEG1-propargyl
CAS Number 1895922-72-1 Molecular Weight 215.25
Density N/A Boiling Point N/A
Molecular Formula C10H17NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-Boc-aminooxy-PEG1-propargyl


Boc-aminooxy-PEG1-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Boc-aminooxy-PEG1-propargyl
Synonym More Synonyms

 t-Boc-aminooxy-PEG1-propargyl Biological Activity

Description Boc-aminooxy-PEG1-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

 Chemical & Physical Properties

Molecular Formula C10H17NO4
Molecular Weight 215.25

 Synonyms

MFCD29764325
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