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2100306-58-7

2100306-58-7 structure
2100306-58-7 structure
  • Name: DBCO-NHCO-PEG4-NHS ester
  • Chemical Name: DBCO-NHCO-PEG4-NHS ester
  • CAS Number: 2100306-58-7
  • Molecular Formula: C34H39N3O10
  • Molecular Weight: 649.69
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2020-04-07 11:32:21
  • Modify Date: 2024-01-15 16:26:48
  • DBCO-NHCO-PEG4-NHS ester ester is a MMP-2- and cathepsin B- (CatB) cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name DBCO-NHCO-PEG4-NHS ester
Description DBCO-NHCO-PEG4-NHS ester ester is a MMP-2- and cathepsin B- (CatB) cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Thornlow DN, et al. Dual Site-Specific Antibody Conjugates for Sequential and Orthogonal Cargo Release. Bioconjug Chem. 2019 Jun 19;30(6):1702-1710.

Molecular Formula C34H39N3O10
Molecular Weight 649.69
Hazard Codes Xi