1840886-10-3

1840886-10-3 structure

Name: DBCO-PEG4-amine
Chemical Name: DBCO-PEG4-amine
CAS Number: 1840886-10-3
Molecular Formula: C₂₉H₃₇N₃O₆
Molecular Weight: 523.62
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2020-04-07 20:34:21
Modify Date: 2024-01-16 18:42:36
DBCO-PEG4-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-amine can be used in the synthesis of FPM-PEG4-DBCO (a homobifunctional azide-to-azide cross-linker)[1].

Name	DBCO-PEG4-amine

Description	DBCO-PEG4-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-amine can be used in the synthesis of FPM-PEG4-DBCO (a homobifunctional azide-to-azide cross-linker)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References	[1]. Florinas S, et al. A Nanoparticle Platform To Evaluate Bioconjugation and Receptor-Mediated Cell Uptake Using Cross-Linked Polyion Complex Micelles Bearing Antibody Fragments. Biomacromolecules. 2016 May 9;17(5):1818-33.