903546-18-9

903546-18-9 structure

Name: Desmethyl ferroquine
Chemical Name: Desmethyl ferroquine
CAS Number: 903546-18-9
Molecular Formula: C₂₂H₁₄ClFeN₃
Molecular Weight: 411.66
Catalog: Research Areas Infection
Create Date: 2020-04-29 22:29:36
Modify Date: 2024-01-10 17:50:11
Desmethyl ferroquine (SSR97213) is the active and major metabolite of Ferroquine. Ferroquine is an antimalarial. Desmethyl ferroquine shows significant activity against Chloroquine-susceptible and resistant P. falciparum strains[1].

Name	Desmethyl ferroquine

Description	Desmethyl ferroquine (SSR97213) is the active and major metabolite of Ferroquine. Ferroquine is an antimalarial. Desmethyl ferroquine shows significant activity against Chloroquine-susceptible and resistant P. falciparum strains[1].
Related Catalog	Research Areas >> Infection
In Vitro	The estimate of the apparent terminal half-life of Ferroquine is 15.9 days. However, the equally active principal metabolite Desmethyl ferroquine (DMFQ) has a longer t1/2z, with an overall mean estimate of 31.4 days[1].
References	[1]. Supan C, et al. Pharmacokinetics of ferroquine, a novel 4-aminoquinoline, in asymptomatic carriers of Plasmodium falciparum infections. Antimicrob Agents Chemother. 2012 Jun;56(6):3165-73.

Molecular Formula	C₂₂H₁₄ClFeN₃
Molecular Weight	411.66