1334172-64-3

1334172-64-3 structure
1334172-64-3 structure
  • Name: Fmoc-Lys (biotin-PEG4)-OH
  • Chemical Name: Fmoc-Lys (biotin-PEG4)-OH
  • CAS Number: 1334172-64-3
  • Molecular Formula: C42H59N5O11S
  • Molecular Weight: 842.01
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-09 21:04:05
  • Modify Date: 2024-01-09 19:03:00
  • Fmoc-Lys (biotin-PEG4)-OH is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Fmoc-Lys (biotin-PEG4)-OH
Synonyms MFCD21363320
Description Fmoc-Lys (biotin-PEG4)-OH is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

Molecular Formula C42H59N5O11S
Molecular Weight 842.01