Fmoc-Lys (biotin-PEG4)-OH

Modify Date: 2024-01-09 19:03:00

Fmoc-Lys (biotin-PEG4)-OH Structure
Fmoc-Lys (biotin-PEG4)-OH structure
Common Name Fmoc-Lys (biotin-PEG4)-OH
CAS Number 1334172-64-3 Molecular Weight 842.01
Density N/A Boiling Point N/A
Molecular Formula C42H59N5O11S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Fmoc-Lys (biotin-PEG4)-OH


Fmoc-Lys (biotin-PEG4)-OH is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Fmoc-Lys (biotin-PEG4)-OH
Synonym More Synonyms

 Fmoc-Lys (biotin-PEG4)-OH Biological Activity

Description Fmoc-Lys (biotin-PEG4)-OH is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

 Chemical & Physical Properties

Molecular Formula C42H59N5O11S
Molecular Weight 842.01

 Synonyms

MFCD21363320