Name | m-PEG4-CH2-aldehyde |
---|---|
Synonyms | MFCD30458023 |
Description | m-PEG4-CH2-aldehyde is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs. |
---|---|
Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
References |
[1]. Jennifer Riggs-Sauthier, et al. Oligomer-protease inhibitor conjugates. WO2008112289A2. |
Molecular Formula | C11H22O6 |
---|---|
Molecular Weight | 250.29 |
Hazard Codes | Xi |
---|