2093153-86-5

2093153-86-5 structure

Name: m-PEG8-(CH2)12-phosphonic acid
Chemical Name: m-PEG8-C10-phosphonic acid
CAS Number: 2093153-86-5
Molecular Formula: C₂₇H₅₇O₁₁P
Molecular Weight: 588.71
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-13 19:27:35
Modify Date: 2024-01-09 18:36:01
m-PEG8-C10-phosphonic acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Name	m-PEG8-C10-phosphonic acid

Description	m-PEG8-C10-phosphonic acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.