m-PEG8-(CH2)12-phosphonic acid

Modify Date: 2024-01-09 18:36:01

m-PEG8-(CH2)12-phosphonic acid Structure
m-PEG8-(CH2)12-phosphonic acid structure
Common Name m-PEG8-(CH2)12-phosphonic acid
CAS Number 2093153-86-5 Molecular Weight 588.71
Density N/A Boiling Point N/A
Molecular Formula C27H57O11P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG8-(CH2)12-phosphonic acid


m-PEG8-C10-phosphonic acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

 Names

Name m-PEG8-C10-phosphonic acid

 m-PEG8-(CH2)12-phosphonic acid Biological Activity

Description m-PEG8-C10-phosphonic acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.

 Chemical & Physical Properties

Molecular Formula C27H57O11P
Molecular Weight 588.71
Storage condition 2-8°C