152065-54-8
152065-54-8 structure
- Name: Bromo-PEG2-THP
- Chemical Name: Bromo-PEG2-THP
- CAS Number: 152065-54-8
- Molecular Formula: C9H17BrO3
- Molecular Weight: 253.13
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2020-06-01 21:15:23
- Modify Date: 2024-01-10 16:06:31
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Bromo-PEG2-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Bromo-PEG2-THP |
|---|---|
| Synonyms | 2-[2-(2-Bromoéthoxy)éthoxy]tétrahydro-2H-pyrane |
| Description | Bromo-PEG2-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 314.3±37.0 °C at 760 mmHg |
| Molecular Formula | C9H17BrO3 |
| Molecular Weight | 253.13 |
| Flash Point | 126.8±25.0 °C |
| Exact Mass | 252.036102 |
| LogP | 0.95 |
| Appearance | Liquid |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.481 |