1872433-61-8

1872433-61-8 structure
1872433-61-8 structure
  • Name: 1,1,1-Trifluoroethyl-peg5-tos
  • Chemical Name: 1,1,1-Trifluoroethyl-PEG4-Tos
  • CAS Number: 1872433-61-8
  • Molecular Formula: C17H25F3O7S
  • Molecular Weight: 430.44
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 19:25:41
  • Modify Date: 2024-01-04 16:36:44
  • 1,1,1-Trifluoroethyl-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 1,1,1-Trifluoroethyl-PEG4-Tos
Synonyms MFCD29079383
Description 1,1,1-Trifluoroethyl-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C17H25F3O7S
Molecular Weight 430.44