1,1,1-Trifluoroethyl-peg5-tos

Modify Date: 2024-01-04 16:36:44

1,1,1-Trifluoroethyl-peg5-tos Structure
1,1,1-Trifluoroethyl-peg5-tos structure
Common Name 1,1,1-Trifluoroethyl-peg5-tos
CAS Number 1872433-61-8 Molecular Weight 430.44
Density N/A Boiling Point N/A
Molecular Formula C17H25F3O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1,1,1-Trifluoroethyl-peg5-tos


1,1,1-Trifluoroethyl-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1,1,1-Trifluoroethyl-PEG4-Tos
Synonym More Synonyms

 1,1,1-Trifluoroethyl-peg5-tos Biological Activity

Description 1,1,1-Trifluoroethyl-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C17H25F3O7S
Molecular Weight 430.44

 Synonyms

MFCD29079383
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