2320560-36-7

2320560-36-7 structure
2320560-36-7 structure
  • Name: 2-(Azido-PEG3-amido)-1,3-bis(NHS ester)
  • Chemical Name: 2-(Azido-PEG3-amido)-1,3-bis(NHS ester)
  • CAS Number: 2320560-36-7
  • Molecular Formula: C26H38N6O14
  • Molecular Weight: 658.61
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 19:20:54
  • Modify Date: 2024-01-23 23:59:18
  • 2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-(Azido-PEG3-amido)-1,3-bis(NHS ester)
Description 2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C26H38N6O14
Molecular Weight 658.61
Hazard Codes Xi