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2030168-38-6

2030168-38-6 structure
2030168-38-6 structure
  • Name: 3,4-Dibromo-Mal-PEG4-t-butyl ester
  • Chemical Name: 3,4-Dibromo-Mal-PEG4-Boc
  • CAS Number: 2030168-38-6
  • Molecular Formula: C19H29Br2NO8
  • Molecular Weight: 559.24
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 20:54:37
  • Modify Date: 2024-01-08 15:49:56
  • 3,4-Dibromo-Mal-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 3,4-Dibromo-Mal-PEG4-Boc
Synonyms MFCD30527404
Description 3,4-Dibromo-Mal-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C19H29Br2NO8
Molecular Weight 559.24