3,4-Dibromo-Mal-PEG4-t-butyl ester

Modify Date: 2024-01-08 15:49:56

3,4-Dibromo-Mal-PEG4-t-butyl ester Structure
3,4-Dibromo-Mal-PEG4-t-butyl ester structure
Common Name 3,4-Dibromo-Mal-PEG4-t-butyl ester
CAS Number 2030168-38-6 Molecular Weight 559.24
Density N/A Boiling Point N/A
Molecular Formula C19H29Br2NO8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3,4-Dibromo-Mal-PEG4-t-butyl ester


3,4-Dibromo-Mal-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 3,4-Dibromo-Mal-PEG4-Boc
Synonym More Synonyms

 3,4-Dibromo-Mal-PEG4-t-butyl ester Biological Activity

Description 3,4-Dibromo-Mal-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C19H29Br2NO8
Molecular Weight 559.24

 Synonyms

MFCD30527404
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