848242-88-6

848242-88-6 structure
848242-88-6 structure
  • Name: 4-(N-Boc-amino)-1,6-heptanedioic acid
  • Chemical Name: 4-(N-Boc-amino)-1,6-heptanedioic acid
  • CAS Number: 848242-88-6
  • Molecular Formula: C12H21NO6
  • Molecular Weight: 275.30
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 19:04:25
  • Modify Date: 2024-01-11 12:40:55
  • 4-(N-Boc-amino)-1,6-heptanedioic acid is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 4-(N-Boc-amino)-1,6-heptanedioic acid
Description 4-(N-Boc-amino)-1,6-heptanedioic acid is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C12H21NO6
Molecular Weight 275.30
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