4-(N-Boc-amino)-1,6-heptanedioic acid

Modify Date: 2024-01-11 12:40:55

4-(N-Boc-amino)-1,6-heptanedioic acid Structure
4-(N-Boc-amino)-1,6-heptanedioic acid structure
Common Name 4-(N-Boc-amino)-1,6-heptanedioic acid
CAS Number 848242-88-6 Molecular Weight 275.30
Density N/A Boiling Point N/A
Molecular Formula C12H21NO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 4-(N-Boc-amino)-1,6-heptanedioic acid


4-(N-Boc-amino)-1,6-heptanedioic acid is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 4-(N-Boc-amino)-1,6-heptanedioic acid

 4-(N-Boc-amino)-1,6-heptanedioic acid Biological Activity

Description 4-(N-Boc-amino)-1,6-heptanedioic acid is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C12H21NO6
Molecular Weight 275.30