2055048-45-6

2055048-45-6 structure
2055048-45-6 structure
  • Name: Active-Mono-Sulfone-PEG8-acid
  • Chemical Name: Active-mono-sulfone-PEG8-acid
  • CAS Number: 2055048-45-6
  • Molecular Formula: C37H53NO14S
  • Molecular Weight: 767.88
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 12:05:09
  • Modify Date: 2024-02-05 22:50:46
  • Active-mono-sulfone-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Active-mono-sulfone-PEG8-acid
Description Active-mono-sulfone-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C37H53NO14S
Molecular Weight 767.88