Active-Mono-Sulfone-PEG8-acid

Modify Date: 2024-02-05 22:50:46

Active-Mono-Sulfone-PEG8-acid Structure
Active-Mono-Sulfone-PEG8-acid structure
Common Name Active-Mono-Sulfone-PEG8-acid
CAS Number 2055048-45-6 Molecular Weight 767.88
Density N/A Boiling Point N/A
Molecular Formula C37H53NO14S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Active-Mono-Sulfone-PEG8-acid


Active-mono-sulfone-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Active-mono-sulfone-PEG8-acid

 Active-Mono-Sulfone-PEG8-acid Biological Activity

Description Active-mono-sulfone-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C37H53NO14S
Molecular Weight 767.88