1415408-69-3

1415408-69-3 structure

1415408-69-3 structure

Name: Amino-PEG11-acid
Chemical Name: Amino-PEG12-acid
CAS Number: 1415408-69-3
Molecular Formula: C₂₇H₅₅NO₁₄
Molecular Weight: 617.72
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 18:55:15
Modify Date: 2024-04-06 16:25:27
Amino-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Amino-PEG12-acid
Synonyms	MFCD11041150

Description	Amino-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₇H₅₅NO₁₄
Molecular Weight	617.72