Amino-PEG11-acid

Modify Date: 2024-04-06 16:25:27

Amino-PEG11-acid Structure
Amino-PEG11-acid structure
Common Name Amino-PEG11-acid
CAS Number 1415408-69-3 Molecular Weight 617.72
Density N/A Boiling Point N/A
Molecular Formula C27H55NO14 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amino-PEG11-acid


Amino-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Amino-PEG12-acid
Synonym More Synonyms

 Amino-PEG11-acid Biological Activity

Description Amino-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C27H55NO14
Molecular Weight 617.72

 Synonyms

MFCD11041150