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1835759-78-8

1835759-78-8 structure
1835759-78-8 structure
  • Name: Aminooxy-PEG4-propargyl
  • Chemical Name: Aminooxy-PEG4-propargyl
  • CAS Number: 1835759-78-8
  • Molecular Formula: C11H21NO5
  • Molecular Weight: 247.29
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 10:59:04
  • Modify Date: 2024-01-10 11:02:02
  • Aminooxy-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Aminooxy-PEG4-propargyl
Synonyms MFCD29052160
Description Aminooxy-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C11H21NO5
Molecular Weight 247.29
Hazard Codes Xi