Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Azido-PEG1-CH2COO-Cl
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Purity: 95.0%
Stocking Period: 10 Day
Contact: Yang
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79598-49-5

79598-49-5 structure

79598-49-5 structure

Name: Azido-PEG1-CH2COO-Cl
Chemical Name: Azido-PEG1-CH2COO-Cl
CAS Number: 79598-49-5
Molecular Formula: C₄H₆ClN₃O₂
Molecular Weight: 163.56
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 20:11:52
Modify Date: 2025-08-27 10:20:15
Azido-PEG1-CH2COO-Cl (compound 43a) is an alkyl/ether-based PROTAC linker. Azido-PEG1-CH2COO-Cl can be used in the synthesis of PROTAC BRD4 Degrader-1 (HY-133131)[1].

Name	Azido-PEG1-CH2COO-Cl

Description	Azido-PEG1-CH2COO-Cl (compound 43a) is an alkyl/ether-based PROTAC linker. Azido-PEG1-CH2COO-Cl can be used in the synthesis of PROTAC BRD4 Degrader-1 (HY-133131)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
In Vitro	PROTAC BRD4 Degrader-1 is an efficacious BRD4 degrader with an IC50 of 41.8 nM against BRD4 BD1. PROTAC BRD4 Degrader-1 can effectively degrade BRD4 protein and suppress c-Myc expression[1].
References	[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide.Bioorg Med Chem. 2020 Jan 1;28(1):115228.

Molecular Formula	C₄H₆ClN₃O₂
Molecular Weight	163.56

Hazard Codes	Xi

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