Name | Azido-PEG1-CH2COO-Cl |
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Description | Azido-PEG1-CH2COO-Cl (compound 43a) is an alkyl/ether-based PROTAC linker. Azido-PEG1-CH2COO-Cl can be used in the synthesis of PROTAC BRD4 Degrader-1 (HY-133131)[1]. |
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Related Catalog | |
Target |
Alkyl/ether |
In Vitro | PROTAC BRD4 Degrader-1 is an efficacious BRD4 degrader with an IC50 of 41.8 nM against BRD4 BD1. PROTAC BRD4 Degrader-1 can effectively degrade BRD4 protein and suppress c-Myc expression[1]. |
References |
Molecular Formula | C4H6ClN3O2 |
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Molecular Weight | 163.56 |
Hazard Codes | Xi |
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