Top Suppliers:I want be here

2363756-50-5

2363756-50-5 structure
2363756-50-5 structure
  • Name: Azido-PEG12-NHS ester
  • Chemical Name: Azido-PEG12-NHS ester
  • CAS Number: 2363756-50-5
  • Molecular Formula: C31H56N4O16
  • Molecular Weight: 740.79
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-04 12:27:54
  • Modify Date: 2024-01-09 12:36:30
  • Azido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Azido-PEG12-NHS ester
Description Azido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C31H56N4O16
Molecular Weight 740.79