2243566-43-8

2243566-43-8 structure

2243566-43-8 structure

Name: Azido-PEG3-amide-C3-triethoxysilane
Chemical Name: Azido-PEG3-amide-C3-triethoxysilane
CAS Number: 2243566-43-8
Molecular Formula: C₁₈H₃₈N₄O₇Si
Molecular Weight: 450.60
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 18:24:33
Modify Date: 2024-01-23 18:10:42
Azido-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Azido-PEG3-amide-C3-triethoxysilane

Description	Azido-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₈H₃₈N₄O₇Si
Molecular Weight	450.60