Azido-PEG3-amide-C3-triethoxysilane

Modify Date: 2024-01-23 18:10:42

Azido-PEG3-amide-C3-triethoxysilane structure	Common Name	Azido-PEG3-amide-C3-triethoxysilane
	CAS Number	2243566-43-8	Molecular Weight	450.60
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₃₈N₄O₇Si	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Azido-PEG3-amide-C3-triethoxysilane

Azido-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Azido-PEG3-amide-C3-triethoxysilane

Description	Azido-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₈H₃₈N₄O₇Si
Molecular Weight	450.60